Normal IncA expression and fusogenicity of inclusions in Chlamydia trachomatis isolates with the incA I47T mutation

被引：10

作者：

Pannekoek, Y

van der Ende, A

Eijk, PP

van Marle, J

de Witte, MA

Ossewaarde, JM

van den Brule, AJC

Morré, SA

Dankert, J

机构：

[1] Univ Amsterdam, Acad Med Ctr, Dept Med Microbiol, NL-1100 DD Amsterdam, Netherlands

[2] Univ Amsterdam, Acad Med Ctr, Sect Electron Microscopy, NL-1100 DD Amsterdam, Netherlands

[3] Vrije Univ Amsterdam, Med Ctr, Amsterdam, Netherlands

[4] Natl Inst Publ Hlth & Environm, Res Lab Infect Dis, NL-3720 BA Bilthoven, Netherlands

来源：

INFECTION AND IMMUNITY | 2001年 / 69卷 / 07期

关键词：

D O I：

10.1128/IAI.69.7.4654-4656.2001

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

To investigate the correlation between the incA I47T mutation in Chlamydia trachomatis and the nonfusogenic phenotype, the incA genes of 25 isolates were sequenced. Four major sequence types were identified. Seven isolates (28%) had the I47T mutation. Isolates representing the four sequence types expressed incA in the membrane of one large single inclusion. In conclusion, the incA I47T mutation is not associated with the nonfusogenic phenotype.

引用

页码：4654 / 4656

页数：3

共 16 条

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