Analysis of antibiotics in biological samples by capillary electrophoresis

被引：82

作者：

Hernández, M ^{[1
]}

Borrull, F ^{[1
]}

Calull, M ^{[1
]}

机构：

[1] Univ Rovira & Virgili, Dept Quim Analit & Quim Organ, Tarragona 43005, Spain

来源：

TRAC-TRENDS IN ANALYTICAL CHEMISTRY | 2003年 / 22卷 / 07期

关键词：

antibiotics; biological samples; capillary electrophoresis;

D O I：

10.1016/S0165-9936(03)00702-7

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Antibiotics are widely used to treat and prevent diseases in humans and animals. It is therefore important to monitor their residues in biological samples. This is a review of some of the most important antibiotic groups used in medicine: beta-lactam antibiotics (penicillins and cephalosporins); aminoglycosides; quinolones; and, tetracyclines. We describe how capillary electrophoresis (CE) is used to analyze these antibiotics in biological samples. We also discuss how the biological samples are pre-treated before they are analyzed and describe several ways in which the sensitivity of CE systems can be improved. (C) 2003 Published by Elsevier Science B.V.

引用

页码：416 / 427

页数：12

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