Voglibose (Basen® AO-128), one of the most important α-glucosidase inhibitors

被引：131

作者：

Chen, XL ^{[1
]}

Zheng, YG ^{[1
]}

Shen, YC ^{[1
]}

机构：

[1] Zhejiang Univ Technol, Inst Bioengn, Hangzhou 310032, Peoples R China

来源：

CURRENT MEDICINAL CHEMISTRY | 2006年 / 13卷 / 01期

关键词：

voglibose; glucosidase inhibitor; preparation; NIDDM;

D O I：

10.2174/092986706775197962

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

The number of people with diabetes is expected to rise from the current estimated 150 million to 220 million in 2010 and 300 million in 2025, and 90% is Type 2 diabetes or non-insulin dependant diabetes mellitus (NIDDM). Voglibose, one of the most important alpha-glucosidase inhibitors, delays the digestion and absorption of carbohydrates, thereby inhibiting postprandial hyperglycemia and hyperinsulinemia, and is the aid in the treatment of diabetes. In this paper, properties and the preparation of voglibose are reviewed.

引用

页码：109 / 116

页数：8

共 37 条

[1]

Type 1 diabetes: new perspectives on disease pathogenesis and treatment [J].