Biomedical and clinical applications of immunoassays and immunosensors for tumor markers

被引：422

作者：

Wu, Jie

Fu, Zhifeng

Yan, Feng ^{[1
]}

Ju, Huangxian

机构：

[1] Nanjing Univ, Dept Chem, Minist Educ China, Key Lab Analyt Chem Life Sci, Nanjing 210093, Peoples R China

[2] Jiangsu Inst Canc Prevent & Cure, Nanjing 210009, Peoples R China

来源：

TRAC-TRENDS IN ANALYTICAL CHEMISTRY | 2007年 / 26卷 / 07期

基金：

中国国家自然科学基金;

关键词：

biosensor; clinical diagnosis; immunoassay; immunosensor; tumor marker;

D O I：

10.1016/j.trac.2007.05.007

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Cancer is one of the most threatening diseases for human beings. The detection of tumor biomarkers, including serum tumor markers and potential prognostic factors for tumors, plays an important role in clinical diagnoses and evaluation of treatment for patients with certain tumor-associated diseases. Many immunoassay methods and immunosensors are being developed for detection of tumor-related biomarkers. This review summarizes the state of immunoassay technologies for tumor diagnostics. It also focuses on a growing number of applications and progress in immunosensors for tumor markers. It covers the basic principles and biomedical and clinical applications of immunosensors, and indicates the future prospects in this field. (c) 2007 Elsevier Ltd. All rights reserved.

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收藏

页码：679 / 688

页数：10

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