Various cytokines and soluble growth factors upon interaction with their membrane receptors are responsible for inducing cellular proliferation, differentiation, movement, and protection from anoikis (a planned suicide activated by normal cells in absence of attachment to neighboring cells or extracellular matrix (EMC)). Among those soluble factors a major position is exerted by hepatocyte growth factor (HGF) together with its receptor MET and macrophage-stimulating protein (MSP) in cooperation with its receptor RON.
机构:
Univ Calif San Francisco, Dept Biochem & Biophys, San Francisco, CA 94143 USAUniv Calif San Francisco, Dept Biochem & Biophys, San Francisco, CA 94143 USA
Hanahan, D
;
Weinberg, RA
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机构:Univ Calif San Francisco, Dept Biochem & Biophys, San Francisco, CA 94143 USA
机构:
Univ Calif San Francisco, Dept Biochem & Biophys, San Francisco, CA 94143 USAUniv Calif San Francisco, Dept Biochem & Biophys, San Francisco, CA 94143 USA
Hanahan, D
;
Weinberg, RA
论文数: 0引用数: 0
h-index: 0
机构:Univ Calif San Francisco, Dept Biochem & Biophys, San Francisco, CA 94143 USA