A new synthesis of combretastatins A-4 and AVE-8062A

被引：58

作者：

Lara-Ochoa, Francisco ^{[1
]}

Espinosa-Perez, Georgina ^{[1
]}

机构：

[1] Univ Nacl Autonoma Mexico, Inst Quim, Mexico City 04510, DF, Mexico

来源：

TETRAHEDRON LETTERS | 2007年 / 48卷 / 39期

关键词：

D O I：

10.1016/j.tetlet.2007.07.151

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Combretastatins A-4 and AVE-8062A have been synthesized by coupling 3,4,5-trimethoxyphenylacetylene with the corresponding iodomethoxyphenol and bromomethoxyaniline, followed by hydrolysis of the thermally-stable Ti(II)-alkyne complexes. (c) 2007 Elsevier Ltd. All rights reserved.

引用

页码：7007 / 7010

页数：4

共 17 条

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