Chiral ligands derived from Abrine .3. Asymmetric Pictet-Spengler reaction of Abrine methyl ester and synthesis of chiral 1,2,3,4-tetrahydro-beta-carbolines as promoters in addition of diethylzinc toward aromatic aldehydes

被引：26

作者：

Dai, WM ^{[1
]}

Zhu, HJ ^{[1
]}

Hao, XJ ^{[1
]}

机构：

[1] CHINESE ACAD SCI,KUNMING INST BOT,KUNMING 650204,YUNNAN,PEOPLES R CHINA

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 33期

关键词：

D O I：

10.1016/0040-4039(96)01290-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Asymmetric Pictet-Spengler reaction of a number of aldehydes with Abrine methyl ester (1) was performed at room temperature to furnish mainly 3 and high ee was obtained in enantioselective addition of Et(2)Zn with PhCHO catalyzed by chiral 1,2,3,4-tetrahydro-beta-carboline derivatives 5 synthesized from 3. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：5971 / 5974

页数：4

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