Chiral ligands derived from Abrine .2. Oxazolidines as promoters for enantioselective addition of diethylzinc toward aromatic aldehydes

被引：38

作者：

Dai, WM ^{[1
]}

Zhu, HJ ^{[1
]}

Hao, XJ ^{[1
]}

机构：

[1] CHINESE ACAD SCI,KUNMING INST BOT,KUNMING 650204,PEOPLES R CHINA

来源：

TETRAHEDRON-ASYMMETRY | 1996年 / 7卷 / 05期

关键词：

D O I：

10.1016/0957-4166(96)00133-4

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A number of indole-containing chiral oxazolidines 2a-i have been synthesized from Abrine readily available from the seeds of Abrus precatorius. Catalysis of these oxazolidines for the addition of diethylzinc toward benzaldehyde was examined. A significant role of the substituent(s) in the catalyst on the degree of asymmetric induction was noted. Moderate enantioselectivity up to 59.8% was recorded. Copyright (C) 1996 Published by Elsevier Science Ltd

引用

页码：1245 / 1248

页数：4

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