Stress proteins and immunity mediated by cytotoxic T lymphocytes

被引：85

作者：

Schild, H ^{[1
]}

Arnold-Schild, D ^{[1
]}

Lammert, E ^{[1
]}

Rammensee, HG ^{[1
]}

机构：

[1] Univ Tubingen, Dept Immunol, Inst Cell Biol, D-72076 Tubingen, Germany

来源：

CURRENT OPINION IN IMMUNOLOGY | 1999年 / 11卷 / 01期

关键词：

D O I：

10.1016/S0952-7915(99)80019-3

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Chaperone molecules, including members of the heat shock protein family, are able to stimulate alpha beta and gamma delta T cells as well as natural killer cells. For alpha beta T cells, specificity is induced by chaperone-assisted peptides; this has lead to detailed investigations of peptides that bind to these chaperones and their possible role in antigen presentation.

引用

页码：109 / 113

页数：5

共 56 条

[31] Tumor immunogenicity is determined by the mechanism of cell death via induction of heat shock protein expression [J].

Melcher, A ;

Todryk, S ;

Hardwick, N ;

Ford, M ;

Jacobson, M ;

Vile, RG .

NATURE MEDICINE, 1998, 4 (05) :581-587

[32]

MENORET A, 1995, J IMMUNOL, V155, P740

[33] CD3(-) LARGE GRANULAR LYMPHOCYTES RECOGNIZE A HEAT-INDUCIBLE IMMUNOGENIC DETERMINANT ASSOCIATED WITH THE 72-KD HEAT-SHOCK PROTEIN ON HUMAN SARCOMA-CELLS [J].

MULTHOFF, G ;

BOTZLER, C ;

WIESNET, M ;

EISSNER, G ;

ISSELS, R .

BLOOD, 1995, 86 (04) :1374-1382

[34] A STRESS-INDUCIBLE 72-KDA HEAT-SHOCK PROTEIN (HSP72) IS EXPRESSED ON THE SURFACE OF HUMAN TUMOR-CELLS, BUT NOT ON NORMAL-CELLS [J].

MULTHOFF, G ;

BOTZLER, C ;

WIESNET, M ;

MULLER, E ;

MEIER, T ;

WILMANNS, W ;

ISSELS, RD .

INTERNATIONAL JOURNAL OF CANCER, 1995, 61 (02) :272-279

[35] Biochemical, cell biological and immunological issues surrounding the endoplasmic reticulum chaperone GRP94/gp96 [J].

Nicchitta, CV .

CURRENT OPINION IN IMMUNOLOGY, 1998, 10 (01) :103-109

[36] Isolation of an immunodominant viral peptide that is endogenously bound to the stress protein GP96/GRP94 [J].

Nieland, TJF ;

Tan, MCAA ;

MonneevanMuijen, M ;

Koning, F ;

Kruisbeek, AM ;

vanBleek, GM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (12) :6135-6139

[37] STIMULATION OF A MAJOR SUBSET OF LYMPHOCYTES EXPRESSING T-CELL RECEPTOR-GAMMA-DELTA BY AN ANTIGEN DERIVED FROM MYCOBACTERIUM-TUBERCULOSIS [J].

OBRIEN, RL ;

HAPP, MP ;

DALLAS, A ;

PALMER, E ;

KUBO, R ;

BORN, WK .

CELL, 1989, 57 (04) :667-674

[38] Purification of immunogenic heat shock protein 70-peptide complexes by ADP-affinity chromatography [J].

Peng, P ;

Menoret, A ;

Srivastava, PK .

JOURNAL OF IMMUNOLOGICAL METHODS, 1997, 204 (01) :13-21

[39] Synthetic peptides non-covalently bound to bacterial hsp 70 elicit peptide-specific T-cell responses in vivo [J].

Roman, E ;

Moreno, C .

IMMUNOLOGY, 1996, 88 (04) :487-492

[40] Delayed-type hypersensitity elicited by synthetic peptides complexed with Mycobacterium tuberculosis hsp 70 [J].

Roman, E ;

Moreno, C .

IMMUNOLOGY, 1997, 90 (01) :52-56

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