Stress proteins and immunity mediated by cytotoxic T lymphocytes

被引：85

作者：

Schild, H ^{[1
]}

Arnold-Schild, D ^{[1
]}

Lammert, E ^{[1
]}

Rammensee, HG ^{[1
]}

机构：

[1] Univ Tubingen, Dept Immunol, Inst Cell Biol, D-72076 Tubingen, Germany

来源：

CURRENT OPINION IN IMMUNOLOGY | 1999年 / 11卷 / 01期

关键词：

D O I：

10.1016/S0952-7915(99)80019-3

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Chaperone molecules, including members of the heat shock protein family, are able to stimulate alpha beta and gamma delta T cells as well as natural killer cells. For alpha beta T cells, specificity is induced by chaperone-assisted peptides; this has lead to detailed investigations of peptides that bind to these chaperones and their possible role in antigen presentation.

引用

页码：109 / 113

页数：5

共 56 条

[51]

UDONO H, 1994, J IMMUNOL, V152, P5398

[52] HEAT-SHOCK PROTEIN-70 ASSOCIATED PEPTIDES ELICIT SPECIFIC CANCER IMMUNITY [J].

UDONO, H ;

SRIVASTAVA, PK .

JOURNAL OF EXPERIMENTAL MEDICINE, 1993, 178 (04) :1391-1396

[53]

von Ardenne M, 1975, Radiobiol Radiother (Berl), V16, P99

[54] Structural transitions accompanying the activation of peptide binding to the endoplasmic reticulum Hsp90 chaperone GRP94 [J].

Wearsch, PA ;

Voglino, L ;

Nicchitta, CV .

BIOCHEMISTRY, 1998, 37 (16) :5709-5719

[55] Interaction of endoplasmic reticulum chaperone GRP94 with peptide substrates is adenine nucleotide-independent [J].

Wearsch, PA ;

Nicchitta, CV .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (08) :5152-5156

[56] Structural analysis of substrate binding by the molecular chaperone DnaK [J].

Zhu, XT ;

Zhao, X ;

Burkholder, WF ;

Gragerov, A ;

Ogata, CM ;

Gottesman, ME ;

Hendrickson, WA .

SCIENCE, 1996, 272 (5268) :1606-1614

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