The stomach as a site for anthocyanins absorption from food

被引：243

作者：

Passamonti, S

Vrhovsek, U

Vanzo, A

Mattivi, F

机构：

[1] Univ Trieste, Dipartimento Biochim Biofis & Chim Macromol, I-34127 Trieste, Italy

[2] Ist Agr San Michele, Ctr Sperimentale, Dipartimento Lab Anal & Ric, I-38010 San Michele All Adige, Italy

来源：

FEBS LETTERS | 2003年 / 544卷 / 1-3期

关键词：

anthocyanin; gastric absorption; digestive tract; HPLC; mass spectrometry; Vitis vinifera;

D O I：

10.1016/S0014-5793(03)00504-0

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The ability of anthocyanins to permeate the gastric mucosa can be suggested as a possible explanation of the fast kinetics of plasma appearance of anthocyanins in rats and humans. This paper presents an in vivo experiment aimed to prove the involvement of the stomach in the absorption of grape anthocyanins in rats. The required analytical selectivity and sensitivity was achieved by high-performance liquid chromatography, diode array detection and mass spectrometry. Malvidin 3-glucoside appeared in both portal and systemic plasma after only 6 min. The average concentrations measured in portal and systemic plasma were 0.650 +/- 0.162 muM and 0.234 +/- 0.083 muM (mean +/- S.E.M.), respectively. (C) 2003 Published by Elsevier Science B.V. on behalf of the Federation of European Biochemical Societies.

引用

页码：210 / 213

页数：4

共 24 条

[11] Orally administered delphinidin 3-rutinoside and cyanidin 3-rutinoside are directly absorbed in rats and humans and appear in the blood as the intact forms [J].