Manufacturing of nanochannels with controlled dimensions using protease nanolithography

被引：19

作者：

Ionescu, RE ^{[1
]}

Marks, RS ^{[1
]}

Gheber, LA ^{[1
]}

机构：

[1] Ben Gurion Univ Negev, Dept Biotechnol Engn, IL-84105 Beer Sheva, Israel

来源：

NANO LETTERS | 2005年 / 5卷 / 05期

关键词：

D O I：

10.1021/nl0500510

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The feasibility of creating nanometer scale depressions in biological substrates using active enzymes delivered with scanning probe microscopes has been previously demonstrated by us and other groups. Here we present a comprehensive study revealing the dependence of channels dimensions on the parameters of the "writing" process and provide a simple way to precisely control their dimensions. Such nanochannels may be used in nanofluidic biochip applications.

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收藏

页码：821 / 827

页数：7

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