Mechanisms of pathogenesis: evasion of killing by polymorphonuclear leukocytes

被引：46

作者：

Allen, LAH

机构：

[1] Univ Iowa, Dept Med, Iowa City, IA 52241 USA

[2] Univ Iowa, Inflammat Program, Iowa City, IA 52241 USA

[3] Vet Adm Med Ctr, Iowa City, IA 52241 USA

来源：

MICROBES AND INFECTION | 2003年 / 5卷 / 14期

关键词：

phagocytosis; NADPH oxidase; phagosome maturation; macrophage; neutrophil;

D O I：

10.1016/j.micinf.2003.09.011

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Few microorganisms evade killing by neutrophils. Summarized here are the mechanisms used by Yersinia, group A streptococci, Helicobacter Ehrlichia and Francisella to block phagocytosis, disrupt phagosome maturation or perturb the respiratory burst. Also discussed are mechanisms used by neutrophils to control organisms that replicate inside macrophages. (C) 2003 Editions scientifiques et medicales Elsevier SAS. All rights reserved.

引用

收藏

页码：1329 / 1335

页数：7

相关论文

共 37 条

[11] Pathogenesis of group A streptococcal infections [J].

Cunningham, MW .

CLINICAL MICROBIOLOGY REVIEWS, 2000, 13 (03) :470-+

[12] VIRULENCE FACTORS OF THE FAMILY LEGIONELLACEAE [J].

DOWLING, JN ;

SAHA, AK ;

GLEW, RH .

MICROBIOLOGICAL REVIEWS, 1992, 56 (01) :32-60

[13] GROWTH OF FRANCISELLA-TULARENSIS LVS IN MACROPHAGES - THE ACIDIC INTRACELLULAR COMPARTMENT PROVIDES ESSENTIAL IRON REQUIRED FOR GROWTH [J].

FORTIER, AH ;

LEIBY, DA ;

NARAYANAN, RB ;

ASAFOADJEI, E ;

CRAWFORD, RM ;

NACY, CA ;

MELTZER, MS .

INFECTION AND IMMUNITY, 1995, 63 (04) :1478-1483

[14] Endoplasmic reticulum-mediated phagocytosis is a mechanism of entry into macrophages [J].

Gagnon, E ;

Duclos, S ;

Rondeau, C ;

Chevet, E ;

Cameron, PH ;

Steele-Mortimer, O ;

Paiement, J ;

Bergeron, JJM ;

Desjardins, M .

CELL, 2002, 110 (01) :119-131

[15] Intracellular parasitism by the human granulocytic ehrlichiosis bacterium through the P-selectin ligand, PSGL-1 [J].

Herron, MJ ;

Nelson, CM ;

Larson, J ;

Snapp, KR ;

Kansas, GS ;

Goodman, JL .

SCIENCE, 2000, 288 (5471) :1653-1656

[16] THE EFFECT OF OXYGEN-DEPENDENT ANTIMICROBIAL SYSTEMS ON STRAINS OF LEGIONELLA-PNEUMOPHILA OF DIFFERENT VIRULENCE [J].

JEPRAS, RI ;

FITZGEORGE, RB .

JOURNAL OF HYGIENE, 1986, 97 (01) :61-69

[17]

KATZ SM, 1982, LAB INVEST, V46, P24

[18] Evasion of human innate and acquired immunity by a bacterial homolog of CD11b that inhibits opsonophagocytosis [J].

Lei, BF ;

DeLeo, FR ;

Hoe, NP ;

Graham, MR ;

Mackie, SM ;

Cole, RL ;

Liu, MY ;

Hill, HR ;

Low, DE ;

Federle, MJ ;

Scott, JR ;

Musser, JM .

NATURE MEDICINE, 2001, 7 (12) :1298-1305

[19]

LOFGREN S, 1983, INFECT IMMUN, V39, P715

[20] Shigella flexneri is trapped in polymorphonuclear leukocyte vacuoles and efficiently killed [J].

MandicMulec, I ;

Weiss, J ;

Zychlinsky, A .

INFECTION AND IMMUNITY, 1997, 65 (01) :110-115

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