Microbial genome mining answers longstanding biosynthetic questions

被引：7

作者：

Crawford, Jason M. ^{[2
]}

Clardy, Jon ^{[1
]}

机构：

[1] Harvard Univ, Sch Med, Dept Biol Chem & Mol Pharmacol, Boston, MA 02215 USA

[2] Yale Univ, Dept Chem, Inst Biol Chem, New Haven, CT 06520 USA

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 2012年 / 109卷 / 20期

关键词：

METABOLITE; MECHANISM; ACID;

D O I：

10.1073/pnas.1205361109

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

收藏

页码：7589 / 7590

页数：2

相关论文

共 16 条

[11] Natural Products As Sources of New Drugs over the 30 Years from 1981 to 2010
Newman, David J.
Cragg, Gordon M.
[J]. JOURNAL OF NATURAL PRODUCTS, 2012, 75 (03): : 311 - 335
[12] VERIFICATION OF THE MECHANISM OF OXIDATIVE RING EXPANSION IN THE BIOSYNTHESIS OF STIPITATIC ACID BY TALAROMYCES-STIPITATUS
OSULLIVAN, MC
SCHWAB, JM
[J]. BIOORGANIC CHEMISTRY, 1995, 23 (02) : 131 - 143
[13] Advances in Aspergillus secondary metabolite research in the post-genomic era
Sanchez, James F.
Somoza, Amber D.
Keller, Nancy P.
Wang, Clay C. C.
[J]. NATURAL PRODUCT REPORTS, 2012, 29 (03) : 351 - 371
[14] The impact of genomics on the exploitation of the myxobacterial secondary metabolome
Wenzel, Silke C.
Mueller, Rolf
[J]. NATURAL PRODUCT REPORTS, 2009, 26 (11) : 1385 - 1407
[15] Genomics-inspired discovery of natural products
Winter, Jaclyn M.
Behnken, Swantje
Hertweck, Christian
[J]. CURRENT OPINION IN CHEMICAL BIOLOGY, 2011, 15 (01) : 22 - 31
[16] Cyclization of aromatic polyketides from bacteria and fungi
Zhou, Hui
Li, Yanran
Tang, Yi
[J]. NATURAL PRODUCT REPORTS, 2010, 27 (06) : 839 - 868