Failures of post-exposure rabies prophylaxis

被引:115
作者
Wilde, Henry [1 ]
机构
[1] Chulalongkorn Univ, Fac Med, Dept Med, Div Res & Dev,Infectious Dis Unit, Bangkok 10330, Thailand
关键词
rabies post-exposure prophylaxis; efficacy of post-exposure prophylaxis; failures of post-exposure prophylaxis;
D O I
10.1016/j.vaccine.2007.08.054
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Rabies remains a public health problem in many emerging countries. Virtually all is known that should enable us to eliminate this scourge by controlling the disease in canine populations and by diligent provision of WHO recommended post-exposure prophylaxis (PEP). Nevertheless, post-exposure prophylaxis failures do occur. Most common failures are due to deviations from WHO management recommendations and lack of essential biologicals. True failures, where all was done according to WHO-recommendations, are fortunately extremely rare. Presented are seven such deaths. Other examples of common management deviations that resulted in deaths are also shown. (c) 2007 Elsevier Ltd. All rights reserved.
引用
收藏
页码:7605 / 7609
页数:5
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