Fluorescence resonance energy transfer between a quantum dot donor and a dye acceptor attached to DNA

被引:141
作者
Zhou, DJ
Piper, JD
Abell, C
Klenerman, D
Kang, DJ
Ying, LM
机构
[1] Univ Cambridge, Nanosci Ctr, Cambridge CB3 0FF, England
[2] Univ Cambridge, Dept Chem, Cambridge CB2 1EW, England
[3] Sungkyunkwan Univ, Sungkyunkwan Adv Inst Nanotechnol, Suwon 440746, South Korea
[4] Sungkyunkwan Univ, Dept Phys, Suwon 440746, South Korea
基金
英国生物技术与生命科学研究理事会;
关键词
D O I
10.1039/b508911e
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
We show that direct coupling of a dye-labelled DNA ( acceptor) to a quantum dot (QD) donor significantly reduces the donor acceptor distance and improves the FRET efficiency: a highly efficient FRET (similar to 88%) at a low acceptor-to-donor ratio of 2 has been achieved at the single-molecule level.
引用
收藏
页码:4807 / 4809
页数:3
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