Cardiovascular biology - Creating unique blood vessels

被引:21
作者
Carmeliet, P [1 ]
机构
[1] Univ Leuven VIB, Ctr Transgene Technol & Gene Therapy, B-3000 Louvain, Belgium
关键词
D O I
10.1038/35091178
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
When tissues need more oxygen, they release molecules that encourage blood vessels to grow. The discovery of the first such molecule that is specific to one type of tissue has implications for cancer and heart failure.
引用
收藏
页码:868 / 869
页数:2
相关论文
共 12 条
[1]   Developmental biology - One cell, two fates [J].
Carmeliet, P .
NATURE, 2000, 408 (6808) :43-45
[2]   VEGF gene therapy: stimulating angiogenesis or angioma-genesis? [J].
Carmeliet, P .
NATURE MEDICINE, 2000, 6 (10) :1102-1103
[3]   Mechanisms of angiogenesis and arteriogenesis [J].
Carmeliet, P .
NATURE MEDICINE, 2000, 6 (04) :389-395
[4]   Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions [J].
Carmeliet, P ;
Moons, L ;
Luttun, A ;
Vincenti, V ;
Compernolle, V ;
De Mol, M ;
Wu, Y ;
Bon, F ;
Devy, L ;
Beck, H ;
Scholz, D ;
Acker, T ;
DiPalma, T ;
Dewerchin, M ;
Noel, A ;
Stalmans, I ;
Barra, A ;
Blacher, S ;
Vandendriessche, T ;
Ponten, A ;
Eriksson, U ;
Plate, KH ;
Foidart, JM ;
Schaper, W ;
Charnock-Jones, DS ;
Hicklin, DJ ;
Herbert, JM ;
Collen, D ;
Persico, MG .
NATURE MEDICINE, 2001, 7 (05) :575-583
[5]   Angiogenesis in cancer and other diseases [J].
Carmeliet, P ;
Jain, RK .
NATURE, 2000, 407 (6801) :249-257
[6]  
Dvorak HF, 1999, CURR TOP MICROBIOL, V237, P97
[7]   Vascular endothelial growth factor is essential for corpus luteum angiogenesis [J].
Ferrara, N ;
Chen, H ;
Davis-Smyth, T ;
Gerber, HP ;
Nguyen, TN ;
Peers, D ;
Chisholm, V ;
Hillan, KJ ;
Schwall, RH .
NATURE MEDICINE, 1998, 4 (03) :336-340
[8]   Role of vascular endothelial growth factor in regulation of physiological angiogenesis [J].
Ferrara, N .
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2001, 280 (06) :C1358-C1366
[9]   Identification of an angiogenic mitogen selective for endocrine gland endothelium [J].
LeCouter, J ;
Kowalski, J ;
Foster, J ;
Hass, P ;
Zhang, ZM ;
Dillard-Telm, L ;
Frantz, G ;
Rangell, L ;
DeGuzman, L ;
Keller, GA ;
Peale, F ;
Gurney, A ;
Hillan, KJ ;
Ferrara, N .
NATURE, 2001, 412 (6850) :877-884
[10]   Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration [J].
Oosthuyse, B ;
Moons, L ;
Storkebaum, E ;
Beck, H ;
Nuyens, D ;
Brusselmans, K ;
Van Dorpe, J ;
Hellings, P ;
Gorselink, M ;
Heymans, S ;
Theilmeier, G ;
Dewerchin, M ;
Laudenbach, V ;
Vermylen, P ;
Raat, H ;
Acker, T ;
Vleminckx, V ;
Van den Bosch, L ;
Cashman, N ;
Fujisawa, H ;
Drost, MR ;
Sciot, R ;
Bruyninckx, F ;
Hicklin, DJ ;
Ince, C ;
Gressens, P ;
Lupu, F ;
Plate, KH ;
Robberecht, W ;
Herbert, JM ;
Collen, D ;
Carmeliet, P .
NATURE GENETICS, 2001, 28 (02) :131-138