Potassium trifluoro(organo)borates in rhodium-catalyzed 1,4-additions to α,β-unsaturated esters

被引：43

作者：

Navarre, L ^{[1
]}

Pucheault, M ^{[1
]}

Darses, S ^{[1
]}

Genet, JP ^{[1
]}

机构：

[1] Ecole Natl Super Chim, CNRS, UMR 7573, Lab Synth Select Organ & Prod Nat, F-75231 Paris, France

来源：

TETRAHEDRON LETTERS | 2005年 / 46卷 / 24期

关键词：

borates; asymmetric catalysis; 1,4-addition; rhodium; esters;

D O I：

10.1016/j.tetlet.2005.04.038

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

This letter describes an efficient and enantio selective conjugate addition of highly stable potassium trifluoro(organo)borates to alpha,beta-unsaturated esters. This reaction, catalyzed by chiral rhodium(l) complexes, affords Michael adducts with high yields and enantiomeric excesses up to 96%. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：4247 / 4250

页数：4

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