Synthesis and application in asymmetric C-C bond formation of solution phase ligand libraries of monodentate phosphoramidites

被引：32

作者：

Duursma, A

Lefort, L

Boogers, JAF

de Vries, AHM

de Vries, JG

Minnaard, AJ

Feringa, BL

机构：

[1] Univ Groningen, Stratingh Inst, Dept Organ & Mol Inorgan Chem, NL-9747 AG Groningen, Netherlands

[2] DSM Pharma Chem Adv Synth Catalysis & Dev, NL-6160 MD Geleen, Netherlands

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2004年 / 2卷 / 12期

关键词：

D O I：

10.1039/b404996a

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A library of 96 unique monodentate phosphoramidite ligands has been synthesized in solution and used in the asymmetric conjugate addition of potassium vinyltrifluoroborate to enones resulting in up to 88% ee.

引用

页码：1682 / 1684

页数：3

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