Poly-3-hexyl thiophene Langmuir-Blodgett films for application to glucose biosensor

被引：39

作者：

Singhal, R

Chaubey, A

Kaneto, K

Takashima, W

Malhotra, BD

机构：

[1] Natl Phys Lab, Biomol Elect & Conducting Polymer Res Grp, New Delhi 110012, India

[2] Kyushu Inst Technol, Grad Sch Life Sci & Syst Engn, Iizuka, Fukuoka 8208502, Japan

来源：

BIOTECHNOLOGY AND BIOENGINEERING | 2004年 / 85卷 / 03期

关键词：

LB films; biosensor; glucose oxidase; P3HT;

D O I：

10.1002/bit.10869

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Langmuir-Blodgett films of poly(3-hexyl thiophene) have been prepared by simultaneous entrapment of glucose oxidase and transferred onto the indium-tin-oxide coated glass plates. The films have been characterized by FTIR spectroscopy and detailed response studies have been per-formed with respect to glucose concentration, temperature, and storage time. These P3HT/SA/GOX electrodes have been utilized for glucose estimation from 100-500 mg/dL by amperometric method. The electrodes have been found to have sensitivity of 0.75 nA/mg/dL detection limit of 50 mg/dL and shelf life of about 75 days at 4degreesC. (C) 2004 Wiley Periodicals, Inc.

引用

页码：277 / 282

页数：6

共 34 条

[1] Soluble and processable regioregular poly(3-hexylthiophene) for thin film field-effect transistor applications with high mobility [J].