Copper-mediated cross-coupling of 1,1-dibromo-1-alkenes with dialkyl phosphites: a convenient synthesis of 1-alkenylphosphonates

被引：82

作者：

Evano, Gwilherm ^{[1
]}

Tadiparthi, Krishnaji ^{[1
]}

Couty, Francois ^{[1
]}

机构：

[1] Univ Versailles St Quentin Yvelines, CNRS, UMR 8180, Inst Lavoisier Versailles, F-78035 Versailles, France

来源：

CHEMICAL COMMUNICATIONS | 2011年 / 47卷 / 01期

关键词：

ONE-POT SYNTHESIS; ALPHA; BETA-UNSATURATED PHOSPHONATES; CATALYZED HYDROPHOSPHORYLATION; STEREOSELECTIVE-SYNTHESIS; VINYL PHOSPHONATES; C-N; ALDEHYDES; VINYLPHOSPHONATES; DIBROMIDES; REDUCTION;

D O I：

10.1039/c0cc01617a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An efficient and stereoselective procedure for the preparation of E-1-alkenylphosphonates by copper-mediated cross-coupling between 1,1-dibromo-1-alkenes and dialkyl phosphites is reported. The reaction allows for formal substitution of both bromine atoms, respectively, by an hydrogen and a dialkoxyphosphoryl.

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页码：179 / 181

页数：3

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