Copper-mediated cross-coupling of 1,1-dibromo-1-alkenes with dialkyl phosphites: a convenient synthesis of 1-alkenylphosphonates

被引：82

作者：

Evano, Gwilherm ^{[1
]}

Tadiparthi, Krishnaji ^{[1
]}

Couty, Francois ^{[1
]}

机构：

[1] Univ Versailles St Quentin Yvelines, CNRS, UMR 8180, Inst Lavoisier Versailles, F-78035 Versailles, France

来源：

CHEMICAL COMMUNICATIONS | 2011年 / 47卷 / 01期

关键词：

ONE-POT SYNTHESIS; ALPHA; BETA-UNSATURATED PHOSPHONATES; CATALYZED HYDROPHOSPHORYLATION; STEREOSELECTIVE-SYNTHESIS; VINYL PHOSPHONATES; C-N; ALDEHYDES; VINYLPHOSPHONATES; DIBROMIDES; REDUCTION;

D O I：

10.1039/c0cc01617a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An efficient and stereoselective procedure for the preparation of E-1-alkenylphosphonates by copper-mediated cross-coupling between 1,1-dibromo-1-alkenes and dialkyl phosphites is reported. The reaction allows for formal substitution of both bromine atoms, respectively, by an hydrogen and a dialkoxyphosphoryl.

引用

页码：179 / 181

页数：3

共 54 条

[51] One-Pot Synthesis of Pyrimido[1,6-a]indol-1(2H)-one Derivatives by a Nucleophilic Addition/Cu-Catalyzed N-Arylation/Pd-Catalyzed C-H Activation Sequential Process [J].

Wang, Zhi-Jing ;

Yang, Jian-Guo ;

Yang, Fan ;

Bao, Weiliang .

ORGANIC LETTERS, 2010, 12 (13) :3034-3037

[52] Cul-catalyzed tandem intramolecular amidation using gem-dibromovinyl systems [J].

Yuen, J ;

Fang, YQ ;

Lautens, M .

ORGANIC LETTERS, 2006, 8 (04) :653-656

[53]

Zhao CQ, 2001, ANGEW CHEM INT EDIT, V40, P1929, DOI 10.1002/1521-3773(20010518)40:10<1929::AID-ANIE1929>3.3.CO

[54]

2-D

← 1 2 3 4 5 6 →