Finding the Missing Code of RNA Recognition by PUF Proteins

被引：10

作者：

Chen, Yu ^{[1
]}

Varani, Gabriele ^{[1
]}

机构：

[1] Univ Washington, Dept Chem, Seattle, WA 98195 USA

来源：

CHEMISTRY & BIOLOGY | 2011年 / 18卷 / 07期

关键词：

BINDING PROTEINS; SEQUENCE;

D O I：

10.1016/j.chembiol.2011.07.001

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Pumilio and FBF homology (PUF) proteins represent highly promising candidates for engineering sequence-specific RNA recognition, but were only known to recognize G, A, and U, significantly limiting applications. Two groups (Filipovska et al., 2011; Dong et al., 2011) have now reported the discovery of the cytosine-recognition code for PUF proteins.

引用

收藏

页码：821 / 823

页数：3

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