Cancer in acromegaly

被引:8
作者
Jenkins, P [1 ]
机构
[1] Univ London St Bartholomews Hosp Med Coll, Dept Endocrinol, London EC1A 7BE, England
关键词
D O I
10.1016/S1043-2760(98)00093-9
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
In recent years, it has become increasingly recognized that acromegaly predisposes to a variety of cancers, particularly colorectal and breast cancers, and perhaps haematological malignancies. However, these associations haze been based mostly on small epidemiological surveys, and a propensity towards other malignancies might also become apparent in the future. This review assesses these three malignancies together with those of the thyroid and pi-estate, and discusses their pathogenesis, concentrating on the role of the growth hormone/insulin-like growth factor I (IGF-I) axis.
引用
收藏
页码:360 / 366
页数:7
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