New chiral o-(Phosphinoamido)phenyl sulfoxide ligands in palladium-catalyzed asymmetric allylic alkylations

被引：66

作者：

Hiroi, K ^{[1
]}

Suzuki, Y ^{[1
]}

机构：

[1] Tohoku Coll Pharm, Dept Synthet Organ Chem, Aoba Ku, Sendai, Miyagi 9818558, Japan

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 36期

关键词：

D O I：

10.1016/S0040-4039(98)01384-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new chiral o-(phosphinoamido)phenyl sulfinyl functionality was demonstrated as efficient ligands in palladium-catalyzed asymmetric allylic alkylations. Especially, chiral o-(phosphinoamido)phenyl 2-methoxyl-1-naphthyl sulfoxide was concluded to be the most effective ligand for the asymmetric induction among the known ligands bearing a chiral organosulfur group as the sole chiral source. The mechanism of the asymmetric induction is proposed. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：6499 / 6502

页数：4

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