Foot in mouth: do focal adhesions disassemble by endocytosis?

被引:13
作者
Burridge, K [1 ]
机构
[1] Univ N Carolina, Dept Cell & Dev Biol, Chapel Hill, NC 27599 USA
[2] Univ N Carolina, Lineberger Comprehens Canc Ctr, Chapel Hill, NC 27599 USA
关键词
D O I
10.1038/ncb0505-545
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
How cells disassemble their focal adhesions is not well understood. Now, Ezratty et al. have shown that the GTPase dynamin acts after microtubule targeting of focal adhesions to trigger their disassembly. One intriguing possibility is that dynamin might drive disassembly through endocytosis.
引用
收藏
页码:545 / 547
页数:4
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