Instrumental requirements for non-invasive blood glucose measurement using NIR spectroscopy

被引:13
作者
Arimoto, H
Tarumi, M
Yamada, Y
机构
[1] Natl Inst Adv Ind Sci & Technol, Inst Human Sci & Biomed Engn, Tsukuba, Ibaraki 3058564, Japan
[2] Nikkiso Co Ltd, Haibara, Sizuoka 4210496, Japan
[3] Univ Electrocommun, Dept Mech Engn & Intelligent Syst, Chofu, Tokyo 1828585, Japan
关键词
blood glucose measurement; non-invasive measurement; Monte Carlo simulation; NIR spectroscopy; scattering;
D O I
10.1007/s10043-003-0161-1
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
The magnitude of spectral change in blood glucose measurements with diffuse reflectance spectroscopy is investigated. Spectral change is estimated by simulation of light propagation in skin tissue and measurements of absorbance spectra of aqueous glucose solution. Required sensitivity of spectrophotometers for monitoring change in the blood glucose concentration as small as 10 mg/dL has been obtained using the estimated change in the absorbance spectrum and mean pathlength of light in tissue.
引用
收藏
页码:161 / 165
页数:5
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