blood glucose measurement;
non-invasive measurement;
Monte Carlo simulation;
NIR spectroscopy;
scattering;
D O I:
10.1007/s10043-003-0161-1
中图分类号:
O43 [光学];
学科分类号:
070207 ;
0803 ;
摘要:
The magnitude of spectral change in blood glucose measurements with diffuse reflectance spectroscopy is investigated. Spectral change is estimated by simulation of light propagation in skin tissue and measurements of absorbance spectra of aqueous glucose solution. Required sensitivity of spectrophotometers for monitoring change in the blood glucose concentration as small as 10 mg/dL has been obtained using the estimated change in the absorbance spectrum and mean pathlength of light in tissue.