The plasma membrane of erythrocytes plays a fundamental role in the transport of oxygen, carbon dioxide and nitric oxide and in the maintenance of the reduced state of the heme iron

被引:42
作者
De Rosa, Maria Cristina
Carelli Alinovi, Cristiana
Galtieri, Antonio
Scatena, Roberto
Giardina, Bruno [1 ]
机构
[1] Univ Cattolica Sacro Cuore, Inst Biochem & Clin Biochem, I-00168 Rome, Italy
[2] Univ Cattolica Sacro Cuore, CNR, Inst Chem Mol Recognit, I-00168 Rome, Italy
[3] Univ Messina, Dept Organ & Biol Chem, I-98166 Messina, Italy
关键词
haemoglobin; band; 3; glycolytic enzymes; heterotropic modulation; nitric oxide;
D O I
10.1016/j.gene.2007.02.048
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Here we review new insights into the role of the erythrocyte membrane and the implications of its architecture on the several functions accomplished by the red blood cells. The picture which emerges highlights the capability of Hb and band 3 to modulate erythrocyte metabolism and to meet the needs of the cell. (c) 2007 Elsevier B.V. All rights reserved.
引用
收藏
页码:162 / 171
页数:10
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