Artificial ribozymes and deoxyribozymes

被引：57

作者：

Jäschke, A ^{[1
]}

机构：

[1] Free Univ Berlin, Inst Chem, Dept Chem Biol & Pharm, D-14195 Berlin, Germany

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 2001年 / 11卷 / 03期

关键词：

D O I：

10.1016/S0959-440X(00)00208-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

RNA and DNA molecules with catalytic properties have been isolated by in vitro selection from combinatorial nucleic acid libraries. A broad range of chemical reactions is catalyzed and nucleic acids can accelerate bond formation between small organic substrates. The catalytic performance of nucleic acids can be enhanced by the incorporation of additional functional groups.

引用

页码：321 / 326

页数：6

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