Evolution of DNA and RNA as catalysts for chemical reactions

被引：40

作者：

Jäschke, A ^{[1
]}

Seelig, B ^{[1
]}

机构：

[1] Free Univ Berlin, Dept biol Chem & Pharm, Inst Chem, D-14195 Berlin, Germany

来源：

CURRENT OPINION IN CHEMICAL BIOLOGY | 2000年 / 4卷 / 03期

关键词：

D O I：

10.1016/S1367-5931(00)00086-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In vitro selection from combinatorial nucleic acid libraries has provided new RNA and DNA molecules that have catalytic properties. Catalyzed reactions now go far beyond self-modifying reactions of nucleic acid molecules. The future application of in vitro selected RNA and DNA catalysts in bioorganic synthesis appears promising.

引用

页码：257 / 262

页数：6

共 23 条

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