Asymmetric hydrogenation of ketones with polymer-supported chiral 1,2-diphenylethylenediamine

被引：67

作者：

Li, XG

Chen, WP

Hems, W

King, F

Xiao, JL ^{[2
]}

机构：

[1] Johnson Matthey Synetix, Billingham TS23 1LB, Cleveland, England

[2] Univ Liverpool, Dept Chem, Leverhulme Ctr Innovat Catalysis, Liverpool L69 7ZD, Merseyside, England

来源：

ORGANIC LETTERS | 2003年 / 5卷 / 24期

关键词：

D O I：

10.1021/ol0355837

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A poly(ethylene glycol)-supported chiral diamine (PEG-2), in which the polymer is attached to the phenyl rings, has been synthesized and shown to be highly effective in asymmetric hydrogenation of unfunctionalized aromatic ketones with the possibility of reuse. PEG-2 can also serve as a chiral scaffold on which various immobilized chiral catalysts could be easily built.

引用

页码：4559 / 4561

页数：3

共 36 条

[31] Effect of diphosphine ligands on ruthenium catalysed asymmetric hydrogenation of ketones [J].