Effect of diphosphine ligands on ruthenium catalysed asymmetric hydrogenation of ketones

被引：21

作者：

Subongkoj, S ^{[1
]}

Lange, S ^{[1
]}

Chen, WP ^{[1
]}

Xiao, JL ^{[1
]}

机构：

[1] Univ Liverpool, Dept Chem, Leverhulme Ctr Innovat Catalysis, Liverpool L69 7ZD, Merseyside, England

来源：

JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL | 2003年 / 196卷 / 1-2期

关键词：

diphosphines; bite angles; asymmetric hydrogenation; ketones; ruthenium catalysts; diamines;

D O I：

10.1016/S1381-1169(02)00641-6

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

A series of diphosphines including those that are configurationally flexible were examined in the Ru(II) catalysed enantioselective hydrogenation of 1-acetonaphthone in the presence of a chiral diamine. These ligands were found to exert significant effects on both the activity and enantioselectivity of Ru(II)-diamine catalysts, with the ligand with the smallest bite angle yielding the lowest conversion and the one with largest bite angle yielding the lowest enantioselection. (C) 2002 Elsevier Science B.V. All rights reserved.

引用

页码：125 / 129

页数：5

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