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Roles of homocysteine in cell metabolism -: Old and new functions

被引：173
作者：
Medina, MA [1 ]
Urdiales, JL [1 ]
Amores-Sánchez, MI [1 ]
机构：
[1] Univ Malaga, Fac Ciencias, Dept Biol Mol & Bioquim, E-29071 Malaga, Spain
来源：
EUROPEAN JOURNAL OF BIOCHEMISTRY | 2001年 / 268卷 / 14期
关键词：
homocysteine; folate; cobalamine; cardiovascular disease; neural tube deffect; protein homocysteinylation;
D O I：
10.1046/j.1432-1327.2001.02278.x
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Mild hyperhomocysteinemia has been suggested as a new, independent risk factor for cardiovascular disease. This fact has produced a new, increased interest in the study of homocysteine metabolism and its relation to pathogenesis. This emergent area of biomedical research is reviewed here, stressing the biochemical and metabolic basis of the pathogenicity of increased levels of homocysteine.
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收藏
页码：3871 / 3882
页数：12
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