Rapid and efficient identification of bacteria using gold-nanoparticle -: Poly(para-phenyleneethynylene) constructs

被引：336

作者：

Phillips, Ronnie L. ^{[1
]}

Miranda, Oscar R. ^{[2
]}

You, Chang-Cheng ^{[2
]}

Rotello, Vincent M. ^{[2
]}

Bunz, Uwe H. F. ^{[1
]}

机构：

[1] Georgia Inst Technol, Sch Chem & Biochem, Atlanta, GA 30332 USA

[2] Univ Massachusetts, Dept Chem, Amherst, MA 01003 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2008年 / 47卷 / 14期

关键词：

bacteria; bioanalysis; biosensors; conjugated polymers; gold nanoparticles;

D O I：

10.1002/anie.200703369

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Microbiological intelligence: Simple constructs of hydrophobically functionalized gold nanoarticles and a conjugated polymer (poly(para- phenyleneethynylene, PPE) are able to identify three different strains of E. coli in minutes. The negatively charged bacteria replace the negatively charged conjugated polymers from the positively charged gold nanoparticles (see scheme), differentially restoring the polymer fluorescence. (Figure Presented) © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：2590 / 2594

页数：5

共 28 条

[1] PHYLOGENETIC IDENTIFICATION AND IN-SITU DETECTION OF INDIVIDUAL MICROBIAL-CELLS WITHOUT CULTIVATION [J].

AMANN, RI ;

LUDWIG, W ;

SCHLEIFER, KH .

MICROBIOLOGICAL REVIEWS, 1995, 59 (01) :143-169

[2] Materials science - Food pathogen detection [J].

Batt, Carl A. .

SCIENCE, 2007, 316 (5831) :1579-1580

[3] Deposition of CTAB-terminated nanorods on bacteria to form highly conducting hybrid systems [J].

Berry, V ;

Gole, A ;

Kundu, S ;

Murphy, CJ ;

Saraf, RF .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2005, 127 (50) :17600-17601

[4] ANTIBODY TARGETING TO BACTERIAL-CELLS USING RECEPTOR-SPECIFIC LIGANDS [J].

BERTOZZI, CR ;

BEDNARSKI, MD .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1992, 114 (06) :2242-2245

[5] Identification of an outer membrane protein required for the transport of lipopolysaccharide to the bacterial cell surface [J].

Bos, MP ;

Tefsen, B ;

Geurtsen, J ;

Tommassen, J .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2004, 101 (25) :9417-9422

[6]

BRERETON RG, 2003, CHERNOMETRICS DATA A

[7] Gold nanoparticles: Assembly, supramolecular chemistry, quantum-size-related properties, and applications toward biology, catalysis, and nanotechnology [J].

Daniel, MC ;

Astruc, D .

CHEMICAL REVIEWS, 2004, 104 (01) :293-346

[8] Detection of infectious and toxigenic bacteria [J].

Deisingh, AK ;

Thompson, M .

ANALYST, 2002, 127 (05) :567-581

[9] Towards a comprehensive view of the bacterial cell wall [J].

Dmitriev, B ;

Toukach, F ;

Ehlers, S .

TRENDS IN MICROBIOLOGY, 2005, 13 (12) :569-574

[10] Nosocomial bloodstream infections in United States hospitals: A three-year analysis [J].

Edmond, MB ;

Wallace, SE ;

McClish, DK ;

Pfaller, MA ;

Jones, RN ;

Wenzel, RP .

CLINICAL INFECTIOUS DISEASES, 1999, 29 (02) :239-244

← 1 2 3 →