Organophosphorus chemistry of fullerene:: synthesis and biological effects of organophosphorus compounds of C60

被引：37

作者：

Cheng, FY ^{[1
]}

Yang, XL ^{[1
]}

Fan, CH ^{[1
]}

Zhu, HS ^{[1
]}

机构：

[1] Beijing Inst Technol, Res Ctr Mat Sci, Beijing 100081, Peoples R China

来源：

TETRAHEDRON | 2001年 / 57卷 / 34期

基金：

中国国家自然科学基金;

关键词：

fullerene; organophosphorus compounds; photo-induced; cytotoxicity;

D O I：

10.1016/S0040-4020(01)00670-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Synthesis of novel methanophosphonate and methanophosphonic acid C-60 derivatives was achieved, and their cytotoxicity was studied. In particular, a bis-methanophosphonate C-60 derivative displayed photo-induced cytotoxicity on HeLa cells with IC50 value of 1.30 muM. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：7331 / 7335

页数：5

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