Synthesis of 2-C-trifluoromethyl substituted D-ribose

被引：14

作者：

Eilitz, U

Böttcher, C

Sieler, J

Gockel, S

Haas, A

Burger, K

机构：

[1] Univ Leipzig, Inst Organ Chem, D-04103 Leipzig, Germany

[2] Univ Leipzig, Inst Anorgan Chem, D-04103 Leipzig, Germany

[3] Ruhr Univ Bochum, D-44780 Bochum, Germany

来源：

TETRAHEDRON | 2001年 / 57卷 / 18期

关键词：

trifluoropyruvate; 2-C-trifluoromethyl carbohydrates; fluorinated building blocks;

D O I：

10.1016/S0040-4020(01)00261-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A stereoselective three step synthesis of 2-C-trifluoromethyl D-ribose via McMurry pinacol cross coupling of 2,3-di-O-isopropylidene D-glyceraldehyde and methyl trifluoropyruvate is described. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：3921 / 3925

页数：5

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