Dual-Source Dual-Energy CT With Additional Tin Filtration: Dose and Image Quality Evaluation in Phantoms and In Vivo

被引:163
作者
Primak, Andrew N. [1 ,2 ]
Giraldo, Juan Carlos Ramirez [1 ,3 ]
Eusemann, Christian D. [1 ,2 ]
Schmidt, Bernhard [4 ]
Kantor, Birgit [5 ]
Fletcher, Joel G. [1 ]
McCollough, Cynthia H. [1 ]
机构
[1] Mayo Clin, Dept Radiol, Rochester, MN 55905 USA
[2] Siemens Healthcare USA, Malvern, PA USA
[3] Mayo Clin, Dept Physiol & Biomed Engn, Rochester, MN 55905 USA
[4] Siemens Healthcare, Forchheim, Germany
[5] Mayo Clin, Dept Cardiovasc Dis, Rochester, MN 55905 USA
基金
美国国家卫生研究院;
关键词
CT; oral contrast medium; patient acceptance; COMPUTED-TOMOGRAPHY; INITIAL-EXPERIENCE; MULTIDETECTOR CT; INTRAPLAQUE HEMORRHAGE; PERFORMANCE EVALUATION; PULMONARY-EMBOLISM; URIC-ACID; ANGIOGRAPHY; OPTIMIZATION; DIFFERENTIATION;
D O I
10.2214/AJR.09.3956
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
100231 [临床病理学]; 100902 [航空航天医学];
摘要
OBJECTIVE. The purpose of the study was to determine whether a difference in patient preference exists between iohexol (Omnipaque) and diatrizoate sodium (Gastroview) as oral contrast medium for abdominal-pelvic CT. A secondary objective was to evaluate whether there are significant differences in bowel opacification and adverse effect profile for the two agents. SUBJECTS AND METHODS. From August 2007 through March 2009, 300 patients were enrolled in this prospective study after informed consent was obtained. Eligible patients were identified from those scheduled for outpatient abdominal-pelvic CT. Subjects were randomly assigned to receive one of two oral contrast agents in a double-blinded fashion. Subjects graded the taste using a 5-point scale, and data regarding demographics, total volume, and adverse effects were collected. A direct comparison of 30 mL of each of the two diluted agents in randomized order was then performed. CT images were graded for bowel opacification by two blinded abdominal radiologists. RESULTS. Of 287 subjects who expressed a preference, 233 patients (81%) preferred dilute iohexol compared with 54 patients (19%) who preferred dilute diatrizoate sodium (p < 0.001). Ten patients had no preference, and three patients did not complete the taste comparison study. No difference in bowel opacification was identified between the oral contrast agents (p = 0.27), nor was there a significant difference in adverse effects (p = 0.352). CONCLUSION. Patents preferred dilute iohexol over dilute diatrizoate sodium for oral contrast for abdominal-pelvic CT. There was no significant difference in bowel opacification or adverse effect profile.
引用
收藏
页码:1164 / 1174
页数:11
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