Monte Carlo-aided dosimetry of a new high dose-rate brachytherapy source

被引:211
作者
Daskalov, GM
Loffler, E
Williamson, JF [1 ]
机构
[1] Washington Univ, Sch Med, Mallinckrodt Inst Radiol, Radiat Oncol Ctr, St Louis, MO 63110 USA
[2] Nucletron BV, NL-3900 AX Veenendaal, Netherlands
关键词
dosimetry; high dose-rate brachytherapy; Ir-192; Task Group 43; Monte Carlo simulation;
D O I
10.1118/1.598418
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
In this article we introduce a new high-intensity Ir-192 source design for use in a recently reengineered microSelectron-HDR remote afterloading device for high dose-rate (HDR) brachytherapy. The maximum rigid length and outer diameter of the new source are reduced to 4.95 and 0.90 mm, respectively, compared to 5.50 and 1.10 mm for the previous source design introduced in 1991. In addition, a smaller diameter and more flexible steel cable are used, allowing the source cable to negotiate smaller diameter catheters or more tortuously curved catheters. Using Monte Carlo photon transport simulation, the complete two-dimensional (2-D) dose-rate distribution is calculated over the 0.1-7 cm distance range and are presented both as conventional 2-D Cartesian lookup tables and in the formalism recommended by the American Association of Physicists in Medicine Task Group 43 (TG-43) Report. The dose distribution of this source is very similar to that of its predecessor, except near the source tip and in the shadow of the cable assembly, where differences of 5%-8% are apparent. The accuracy of various methods for extrapolating beyond the tabulated anisotropy functions to short distances is evaluated. It is demonstrated that linear extrapolation from the anisotropy functions defined by TG-43 accurately (+/- 2%) estimates dose rate at short and long distances lying outside the radial distance range of the original measured data from which the anisotropy and radial dose functions were derived. In contrast, the algorithm used on the vendor's planning system results in large calculation errors at distances less than 5 mm. (C) 1998 American Association of Physicists in Medicine. [S0094-2405(98)00511-2].
引用
收藏
页码:2200 / 2208
页数:9
相关论文
共 19 条
[1]  
GLASGOW G P, 1979, Medical Physics (Woodbury), V6, P49, DOI 10.1118/1.594551
[2]   TLD, diode and monte carlo dosimetry of an Ir-192 source for high dose-rate brachytherapy [J].
Kirov, AS ;
Williamson, JF ;
Meigooni, AS ;
Zhu, Y .
PHYSICS IN MEDICINE AND BIOLOGY, 1995, 40 (12) :2015-2036
[3]   Measurement and calculation of heterogeneity correction factors for an Ir-192 high dose-rate brachytherapy source behind tungsten alloy and steel shields [J].
Kirov, AS ;
Williamson, JF ;
Meigooni, AS ;
Zhu, Y .
MEDICAL PHYSICS, 1996, 23 (06) :911-919
[4]   QUANTITATIVE VERIFICATION OF IR-192 PDR AND HDR SOURCE STRUCTURE BY PINHOLE AUTORADIOGRAPHY [J].
KIROV, AS ;
MEIGOONI, AS ;
ZHU, Y ;
VALICENTI, RK ;
WILLIAMSON, JF .
MEDICAL PHYSICS, 1995, 22 (11) :1753-1757
[5]   MONTE-CARLO CALCULATION OF KERMA TO A POINT IN THE VICINITY OF MEDIA INTERFACES [J].
LI, ZF ;
WILLIAMSON, JF ;
PERERA, H .
PHYSICS IN MEDICINE AND BIOLOGY, 1993, 38 (12) :1825-1840
[6]   VOLUME-BASED GEOMETRIC MODELING FOR RADIATION TRANSPORT CALCULATIONS [J].
LI, ZF ;
WILLIAMSON, JF .
MEDICAL PHYSICS, 1992, 19 (03) :667-677
[7]  
LOFFLER E, 1997, COMMUNICATION
[8]   EFFECTIVE ATTENUATION IN WATER OF GAMMA RAYS OF GOLD 198 IRIDIUM 192 CESIUM 137 RADIUM 226 AND COBALT 60 [J].
MEISBERGER, LL ;
KELLER, RJ ;
SHALEK, RJ .
RADIOLOGY, 1968, 90 (05) :953-+
[9]   Anisotropy of an (192)iridium high dose rate source measured with a miniature ionization chamber [J].
Mishra, V ;
Waterman, FM ;
Suntharalingam, N .
MEDICAL PHYSICS, 1997, 24 (05) :751-755
[10]   DOSIMETRY OF INTERSTITIAL BRACHYTHERAPY SOURCES - RECOMMENDATIONS OF THE AAPM RADIATION-THERAPY COMMITTEE TASK GROUP NO 43 [J].
NATH, R ;
ANDERSON, LL ;
LUXTON, G ;
WEAVER, KA ;
WILLIAMSON, JF ;
MEIGOONI, AS .
MEDICAL PHYSICS, 1995, 22 (02) :209-234