Synthesis of oligosaccharides on soluble high-molecular-weight branched polymers in combination with purification by nanofiltration

被引：29

作者：

Majumdar, D ^{[1
]}

Zhu, T ^{[1
]}

Boons, GJ ^{[1
]}

机构：

[1] Univ Georgia, Complex Carbohydrate Res Ctr, Athens, GA 30602 USA

来源：

ORGANIC LETTERS | 2003年 / 5卷 / 20期

关键词：

D O I：

10.1021/ol0352355

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient approach for polymer-supported oligosaccharide synthesis is described whereby branched and high-molecular-weight PEG derivatives are used in combination with purification by nanofiltration. This methodology was applied to the preparation of a tetraglucoside and the tumor-associated antigen Le(x).

引用

页码：3591 / 3594

页数：4

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