Cortical calcium waves in resting newborn mice

被引：210

作者：

Adelsberger, H ^{[1
]}

Garaschuk, O ^{[1
]}

Konnerth, A ^{[1
]}

机构：

[1] Univ Munich, Inst Physiol, D-80336 Munich, Germany

来源：

NATURE NEUROSCIENCE | 2005年 / 8卷 / 08期

关键词：

D O I：

10.1038/nn1502

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Using a new optical fiber - based approach, we demonstrate the presence of recurrent Ca2+ transients in cortical neurons of non-anesthetized newborn mice in vivo. These Ca2+ waves reflect the correlated activity of thousands of cells and were detected only in resting, but not in moving pups. Our results suggest that Ca2+-dependent cortical maturation occurs predominantly during the intermittent sleep-like resting periods that are characteristic for the first days of postnatal life.

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收藏

页码：988 / 990

页数：3

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