Recent advances with liposomes as pharmaceutical carriers

被引:3974
作者
Torchilin, VP [1 ]
机构
[1] Northeastern Univ, Dept Pharmaceut Sci, Boston, MA 02115 USA
关键词
D O I
10.1038/nrd1632
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Liposomes - microscopic phospholipid bubbles with a bilayered membrane structure - have received a lot of attention during the past 30 years as pharmaceutical carriers of great potential. More recently, many new developments have been seen in the area of liposomal drugs - from clinically approved products to new experimental applications, with gene delivery and cancer therapy still being the principal areas of interest. For further successful development of this field, promising trends must be identified and exploited, albeit with a clear understanding of the limitations of these approaches.
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收藏
页码:145 / 160
页数:16
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