The analysis of Neisseria meningitidis proteomes:: Reference maps and their applications

被引:12
作者
Bernardini, Giulia [1 ]
Braconi, Daniela [1 ]
Santucci, Annalisa [1 ]
机构
[1] Univ Siena, Dipartimento Biol Mol, I-53100 Siena, Italy
关键词
microevolution; Neisseria meningitidis; reference map; two-dimensional gel electrophoresis;
D O I
10.1002/pmic.200700094
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Neisseria meningitidis is an encapsulated Gram-negative bacterium responsible for significant morbidity and mortality worldwide. The availability of meningococcal genome sequences in combination with the rapid growth of proteomic techniques and other high-throughput methods, provided new approaches to the analysis of bacterial system biology. This review considers the meningococcal reference maps so far published as a starting point aimed to elucidate bacterial physiology and pathogenicity, paying particular attention to proteins with potential vaccine and diagnostic applications.
引用
收藏
页码:2933 / 2946
页数:14
相关论文
共 106 条
[1]   Rifampin resistance in Neisseria meningitidis due to alterations in membrane permeability [J].
Abadi, FJR ;
Carter, PE ;
Cash, P ;
Pennington, TH .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1996, 40 (03) :646-651
[2]   CLONAL SPREAD OF SEROGROUP-A MENINGOCOCCI - A PARADIGM FOR THE ANALYSIS OF MICROEVOLUTION IN BACTERIA [J].
ACHTMAN, M .
MOLECULAR MICROBIOLOGY, 1994, 11 (01) :15-22
[3]   A COMPARISON OF THE VARIABLE ANTIGENS EXPRESSED BY CLONE-IV-1 AND SUBGROUP-III OF NEISSERIA-MENINGITIDIS SEROGROUP-A [J].
ACHTMAN, M ;
KUSECEK, B ;
MORELLI, G ;
EICKMANN, K ;
WANG, JF ;
CROWE, B ;
WALL, RA ;
HASSANKING, M ;
MOORE, PS ;
ZOLLINGER, W .
JOURNAL OF INFECTIOUS DISEASES, 1992, 165 (01) :53-68
[4]   Proteomic analysis of the sarcosine-insoluble outer membrane fraction of Helicobacter pylori strain 26695 [J].
Baik, SC ;
Kim, KM ;
Song, SM ;
Kim, DS ;
Jun, JS ;
Lee, SG ;
Song, JY ;
Park, JU ;
Kang, HL ;
Lee, WK ;
Cho, MJ ;
Youn, HS ;
Ko, GH ;
Rhee, KH .
JOURNAL OF BACTERIOLOGY, 2004, 186 (04) :949-955
[5]   Proteome analysis of Neisseria meningitidis serogroup A [J].
Bernardini, G ;
Renzone, G ;
Comanducci, M ;
Mini, R ;
Arena, S ;
D'Ambrosio, C ;
Bambini, S ;
Trabalzini, L ;
Grandi, G ;
Martelli, P ;
Achtman, M ;
Scaloni, A ;
Ratti, G ;
Santucci, A .
PROTEOMICS, 2004, 4 (10) :2893-2926
[6]   SECRETOR STATUS, SMOKING AND CARRIAGE OF NEISSERIA-MENINGITIDIS [J].
BLACKWELL, CC ;
WEIR, DM ;
JAMES, VS ;
TODD, WTA ;
BANATVALA, N ;
CHAUDHURI, AKR ;
GRAY, HG ;
THOMSON, EJ ;
FALLON, RJ .
EPIDEMIOLOGY AND INFECTION, 1990, 104 (02) :203-209
[7]  
Bumann D, 2001, PROTEOMICS, V1, P473, DOI 10.1002/1615-9861(200104)1:4<473::AID-PROT473>3.0.CO
[8]  
2-G
[9]   Effectiveness and limitation of two-dimensional gel electrophoresis in bacterial membrane protein proteomics and perspectives [J].
Bunai, K ;
Yamane, K .
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2005, 815 (1-2) :227-236
[10]  
Cash P, 2003, ADV BIOCHEM ENG BIOT, V83, P93