Arisugacins A and B, novel and selective acetylcholinesterase inhibitors from Penicillium sp FO-4259 .2. Structure elucidation

被引：42

作者：

Kuno, F

Shiomi, K

Otoguro, K

Sunazuka, T

Omura, S

机构：

[1] KITASATO INST,BIOL FUNCT RES CTR,MINATO KU,TOKYO 108,JAPAN

[2] KITASATO UNIV,SCH PHARMACEUT SCI,MINATO KU,TOKYO 108,JAPAN

来源：

JOURNAL OF ANTIBIOTICS | 1996年 / 49卷 / 08期

关键词：

D O I：

10.7164/antibiotics.49.748

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The structures of new acetylcholinesterase inhibitors, arisugacins A and B, were elucidated by NMR study. Arisugacins have a (4aR,6aR,12aS,12bS)-4a,6,6a,12,12a,12b-hexahydro-4a, 12a-dihydroxy-4,4,6a,12b-tetramethyl-4H,11H-naphtho[2,1 -b]pyrano[3,4-e]pyran-1,11(SH)-dione moiety in common and 3,4-dimethoxyphenyl or 4-methoxyphenyl residues are attached to C-9 of the moiety.

引用

页码：748 / 751

页数：4

共 12 条

[1]

[Anonymous], J NAT PROD

[2]

HSEU TH, 1982, CRYST STRUCT COMMUN, V11, P199

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