The use of electrochemical impedance spectroscopy for biosensing

被引：642

作者：

Lisdat, F. ^{[1
]}

Schaefer, D. ^{[1
]}

机构：

[1] Wildau Univ Appl Sci, D-15745 Wildau, Germany

来源：

ANALYTICAL AND BIOANALYTICAL CHEMISTRY | 2008年 / 391卷 / 05期

关键词：

impedance; sensor; DNA; antibodies; cells; enzymes;

D O I：

10.1007/s00216-008-1970-7

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

This review introduces the basic concepts and terms associated with impedance and techniques of measuring impedance. The focus of this review is on the application of this transduction method for sensing purposes. Examples of its use in combination with enzymes, antibodies, DNA and with cells will be described. Important fields of application include immune and nucleic acid analysis. Special attention is devoted to the various electrode design and amplification schemes developed for sensitivity enhancement. Electrolyte insulator semiconductor (EIS) structures will be treated separately.

引用

收藏

页码：1555 / 1567

页数：13

相关论文

共 182 条

[1] Ellipsometry measurements and impedance spectroscopy on Langmuir-Blodgett membranes on Si/SiO2 for ion sensitive sensor [J].

Abdelmalek, F ;

Shadaram, M ;

Boushriha, H .

SENSORS AND ACTUATORS B-CHEMICAL, 2001, 72 (03) :208-213

[2] Development of a ligation-based impedimetric DNA sensor for single-nucleotide polymorphism associated with metabolic syndrome [J].

Akagi, Yoshinori ;

Makimura, Megumi ;

Yokoyama, Yoshiyuki ;

Fukazawa, Masaki ;

Fujiki, Satoshi ;

Kadosaki, Masahiro ;

Tanino, Katsurni .

ELECTROCHIMICA ACTA, 2006, 51 (28) :6367-6372

[3] Liposomes labeled with biotin and horseradish peroxidase: A probe for the enhanced amplification of antigen-antibody or oligonucleotide-DNA sensing processes by the precipitation of an insoluble product on electrodes [J].

Alfonta, L ;

Singh, AK ;

Willner, I .

ANALYTICAL CHEMISTRY, 2001, 73 (01) :91-102

[4] Chronopotentiometry and Faradaic impedance spectroscopy as signal transduction methods for the biocatalytic precipitation of an insoluble product on electrode supports: routes for enzyme sensors, immunosensors and DNA sensors [J].

Alfonta, L ;

Bardea, A ;

Khersonsky, O ;

Katz, E ;

Willner, I .

BIOSENSORS & BIOELECTRONICS, 2001, 16 (9-12) :675-687

[5]

Anderson JL, 1996, ANAL CHEM, V68, pR379, DOI 10.1021/a1960015y

[6] FORMATION OF MONOLAYER FILMS BY THE SPONTANEOUS ASSEMBLY OF ORGANIC THIOLS FROM SOLUTION ONTO GOLD [J].

BAIN, CD ;

TROUGHTON, EB ;

TAO, YT ;

EVALL, J ;

WHITESIDES, GM ;

NUZZO, RG .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1989, 111 (01) :321-335

[7]

BALENHOHL T, 2007, ANALYST, V132, P314

[8] Screen-printed electrodes as impedimetric immunosensors for the detection of anti-transglutaminase antibodies in human sera [J].

Balkenhohl, T. ;

Lisdat, F. .

ANALYTICA CHIMICA ACTA, 2007, 597 (01) :50-57

[9] Sensing and amplification of oligonucleotide-DNA interactions by means of impedance spectroscopy: a route to a Tay-Sachs sensor [J].

Bardea, A ;

Patolsky, F ;

Dagan, A ;

Willner, I .

CHEMICAL COMMUNICATIONS, 1999, (01) :21-22

[10]

Bardea A, 2000, ELECTROANAL, V12, P1097, DOI 10.1002/1521-4109(200010)12:14<1097::AID-ELAN1097>3.3.CO

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