The use of electrochemical impedance spectroscopy for biosensing

被引:642
作者
Lisdat, F. [1 ]
Schaefer, D. [1 ]
机构
[1] Wildau Univ Appl Sci, D-15745 Wildau, Germany
关键词
impedance; sensor; DNA; antibodies; cells; enzymes;
D O I
10.1007/s00216-008-1970-7
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
This review introduces the basic concepts and terms associated with impedance and techniques of measuring impedance. The focus of this review is on the application of this transduction method for sensing purposes. Examples of its use in combination with enzymes, antibodies, DNA and with cells will be described. Important fields of application include immune and nucleic acid analysis. Special attention is devoted to the various electrode design and amplification schemes developed for sensitivity enhancement. Electrolyte insulator semiconductor (EIS) structures will be treated separately.
引用
收藏
页码:1555 / 1567
页数:13
相关论文
共 182 条
[11]  
2-O
[12]   STUDY OF IMMUNOGLOBULIN-G THIN-LAYERS OBTAINED BY THE LANGMUIR-BLODGETT METHOD - APPLICATION TO IMMUNOSENSORS [J].
BARRAUD, A ;
PERROT, H ;
BILLARD, V ;
MARTELET, C ;
THERASSE, J .
BIOSENSORS & BIOELECTRONICS, 1993, 8 (01) :39-48
[13]   On the response of a label-free interferon-γ immunosensor utilizing electrochemical impedance spectroscopy [J].
Bart, M ;
Stigter, ECA ;
Stapert, HR ;
de Jong, GJ ;
van Bennekom, WP .
BIOSENSORS & BIOELECTRONICS, 2005, 21 (01) :49-59
[14]   DIRECT DETECTION OF IMMUNOSPECIES BY CAPACITANCE MEASUREMENTS [J].
BATAILLARD, P ;
GARDIES, F ;
JAFFREZICRENAULT, N ;
MARTELET, C ;
COLIN, B ;
MANDRAND, B .
ANALYTICAL CHEMISTRY, 1988, 60 (21) :2374-2379
[15]   Formaldehyde assay by capacitance versus voltage and impedance measurements using bi-layer bio-recognition membrane [J].
Ben Ali, M. ;
Korpan, Y. ;
Gonchar, M. ;
El'skaya, A. ;
Maaref, M. A. ;
Jaffrezic-Renault, N. ;
Martelet, C. .
BIOSENSORS & BIOELECTRONICS, 2006, 22 (05) :575-581
[16]   DNA biosensor using fluorescence microscopy and impedance spectroscopy [J].
Berdat, Daniel ;
Marin, Annick ;
Herrera, Fernando ;
Gijs, Martin A. M. .
SENSORS AND ACTUATORS B-CHEMICAL, 2006, 118 (1-2) :53-59
[17]   An immunological interleukin-6 capacitive biosensor using perturbation with a potentiostatic step [J].
Berggren, C ;
Bjarnason, B ;
Johansson, G .
BIOSENSORS & BIOELECTRONICS, 1998, 13 (10) :1061-1068
[18]  
Berggren C, 2001, ELECTROANAL, V13, P173, DOI 10.1002/1521-4109(200103)13:3<173::AID-ELAN173>3.0.CO
[19]  
2-B
[20]   Capacitance measurements of antibody-antigen interactions in a flow system [J].
Berggren, C ;
Johansson, G .
ANALYTICAL CHEMISTRY, 1997, 69 (18) :3651-3657