Synaptic adhesion molecules

被引：275

作者：

Yamagata, M ^{[1
]}

Sanes, JR ^{[1
]}

Weiner, JA ^{[1
]}

机构：

[1] Washington Univ, Sch Med, Dept Anat & Neurobiol, St Louis, MO 63110 USA

来源：

CURRENT OPINION IN CELL BIOLOGY | 2003年 / 15卷 / 05期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0955-0674(03)00107-8

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Formation, differentiation and plasticity of synapses, the specialized cell-cell contacts through which neurons communicate, all require interactions between pre- and post-synaptic partners. Several synaptically localized adhesion molecules potentially capable of mediating these interactions have been identified recently. Functional studies suggest roles for some of them in target recognition (e.g. SYG-1 and sidekicks), formation and alignment of synaptic specializations (e.g. SynCAM, neuroligin and neurexin), and regulation of synaptic structure and function (e.g. cadherins and syndecan).

引用

页码：621 / 632

页数：12

共 95 条

[51]

Nguyen DNT, 1997, DEVELOPMENT, V124, P3303

[52] Interaction of synaptic scaffolding molecule and β-catenin [J].