Realizing the promise of genomics in biomedical research

被引:89
作者
Guttmacher, AE [1 ]
Collins, FS [1 ]
机构
[1] NHGRI, NIH, Bethesda, MD 20892 USA
来源
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION | 2005年 / 294卷 / 11期
关键词
D O I
10.1001/jama.294.11.1399
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:1399 / 1402
页数:4
相关论文
共 38 条
[1]  
[Anonymous], 2002, GEN WORLD HLTH REP A, P15
[2]   Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case series unselected for family history:: A combined analysis of 22 studies [J].
Antoniou, A ;
Pharoah, PDP ;
Narod, S ;
Risch, HA ;
Eyfjord, JE ;
Hopper, JL ;
Loman, N ;
Olsson, H ;
Johannsson, O ;
Borg, Å ;
Pasini, B ;
Radice, P ;
Manoukian, S ;
Eccles, DM ;
Tang, N ;
Olah, E ;
Anton-Culver, H ;
Warner, E ;
Lubinski, J ;
Gronwald, J ;
Gorski, B ;
Tulinius, H ;
Thorlacius, S ;
Eerola, H ;
Nevanlinna, H ;
Syrjäkoski, K ;
Kallioniemi, OP ;
Thompson, D ;
Evans, C ;
Peto, J ;
Lalloo, F ;
Evans, DG ;
Easton, DF .
AMERICAN JOURNAL OF HUMAN GENETICS, 2003, 72 (05) :1117-1130
[3]   Multiple rare Alleles contribute to low plasma levels of HDL cholesterol [J].
Cohen, JC ;
Kiss, RS ;
Pertsemlidis, A ;
Marcel, YL ;
McPherson, R ;
Hobbs, HH .
SCIENCE, 2004, 305 (5685) :869-872
[4]   With the finished human genome in hand, what next? [J].
Julio Collado-Vides ;
Arturo Medrano-Soto ;
Maria Teresa Tusié-Luna .
Genome Biology, 4 (7)
[5]   A vision for the future of genomics research [J].
Collins, FS ;
Green, ED ;
Guttmacher, AE ;
Guyer, MS .
NATURE, 2003, 422 (6934) :835-847
[6]   The human genome project: Lessons from large-scale biology [J].
Collins, FS ;
Morgan, M ;
Patrinos, A .
SCIENCE, 2003, 300 (5617) :286-290
[7]   The case for a US prospective cohort study of genes and environment [J].
Collins, FS .
NATURE, 2004, 429 (6990) :475-477
[8]   The genomics of malaria infection [J].
Coppel, RL ;
Roos, DS ;
Bozdech, Z .
TRENDS IN PARASITOLOGY, 2004, 20 (12) :553-557
[9]   Definition and clinical importance of haplotypes [J].
Crawford, DC ;
Nickerson, DA .
ANNUAL REVIEW OF MEDICINE, 2005, 56 :303-+
[10]   Drug discovery: A historical perspective [J].
Drews, J .
SCIENCE, 2000, 287 (5460) :1960-1964