A concise, efficient route to fumitremorgins

被引：26

作者：

Bailey, PD ^{[1
]}

Cochrane, PJ

Lorenz, K

Collier, ID

Pearson, DPJ

Rosair, GM

机构：

[1] Heriot Watt Univ, Dept Chem, Edinburgh EH14 4AS, Midlothian, Scotland

[2] Zeneca Agrochem, Jealotts Hill Res Stn, Bracknell RG42 6EY, Berks, England

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 01期

关键词：

alkaloids; anti-tumour; indoles; Pictet-Spengler;

D O I：

10.1016/S0040-4039(00)01899-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Using the kinetically controlled Pictet-Spengler reaction, we have developed a three-step, diastereoselective and enantiospecific synthesis of the natural product demethoxy-fumitremorgin C in 21% overall yield. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：113 / 115

页数：3

共 25 条

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