Protein ubiquitylation and synaptic function

被引：4

作者：

Cremona, O

Collesi, C

Raiteri, E

机构：

[1] Univ Vita Salute San Raffaele, San Raffaele Sci Inst, I-20132 Milan, Italy

[2] Univ Piemonte Orientale A Avogadro, I-28100 Novara, Italy

来源：

MYASTHENIA GRAVIS AND RELATED DISORDERS: BIOMCHEMICAL BASIS FOR DISEASE OF THE NEUROMUSCULAR JUNCTION | 2003年 / 998卷

关键词：

ubiquitin; synapse; neurotransmitter release; synaptic vesicle recycling;

D O I：

10.1196/annals.1254.006

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Conjugation of ubiquitin to proteins is a well-established signal to regulate an ever expanding range of cellular processes. Here, we discuss recent findings that deeply link ubiquitin signaling to synaptic activity.

引用

页码：33 / 40

页数：8

共 62 条

[41] The anaphase-promoting complex: New subunits and regulators [J].

Page, AM ;

Hieter, P .

ANNUAL REVIEW OF BIOCHEMISTRY, 1999, 68 :583-609

[42] Ubiquitin in chains [J].

Pickart, CM .

TRENDS IN BIOCHEMICAL SCIENCES, 2000, 25 (11) :544-548

[43] Mechanisms underlying ubiquitination [J].

Pickart, CM .

ANNUAL REVIEW OF BIOCHEMISTRY, 2001, 70 :503-533

[44] A single motif responsible for ubiquitin recognition and monoubiquitination in endocytic proteins [J].

Polo, S ;

Sigismund, S ;

Faretta, M ;

Guidi, M ;

Capua, MR ;

Bossi, G ;

Chen, H ;

De Camilli, P ;

Di Fiore, PP .

NATURE, 2002, 416 (6879) :451-455

[45] Mechanism of ubiquitin recognition by the CUE domain of Vps9p [J].

Prag, G ;

Misra, S ;

Jones, EA ;

Ghirlando, R ;

Davies, BA ;

Horazdovsky, BF ;

Hurley, JH .

CELL, 2003, 113 (05) :609-620

[46] Intragenic deletion in the gene encoding ubiquitin carboxy-terminal hydrolase in gad mice [J].

Saigoh, K ;

Wang, YL ;

Suh, TG ;

Yamanishi, T ;

Sakai, Y ;

Kiyosawa, H ;

Harada, T ;

Ichihara, N ;

Wakana, S ;

Kikuchi, T ;

Wada, K .

NATURE GENETICS, 1999, 23 (01) :47-51

[47] Numb is an endocytic protein [J].

Santolini, E ;

Puri, C ;

Salcini, AE ;

Gagliani, MC ;

Pelicci, PG ;

Tacchetti, C ;

Di Fiore, PP .

JOURNAL OF CELL BIOLOGY, 2000, 151 (06) :1345-1351

[48] Postsynaptic signaling and plasticity mechanisms [J].

Sheng, M ;

Kim, MJ .

SCIENCE, 2002, 298 (5594) :776-780

[49] A ubiquitin-binding motif required for intramolecular monoubiquitylation, the CUE domain [J].

Shih, SC ;

Prag, G ;

Francis, SA ;

Sutanto, MA ;

Hurley, JH ;

Hicke, L .

EMBO JOURNAL, 2003, 22 (06) :1273-1281

[50] Ataxin-1 with an expanded glutamine tract alters nuclear matrix-associated structures [J].

Skinner, PJ ;

Koshy, BT ;

Cummings, CJ ;

Klement, IA ;

Helin, K ;

Servadio, A ;

Zoghbi, HY ;

Orr, HT .

NATURE, 1997, 389 (6654) :971-974

← 1 2 3 4 5 6 7 →