Uniform-sized molecularly imprinted polymers for β-estradiol

被引:18
作者
Haginaka, J [1 ]
Sanbe, H [1 ]
机构
[1] Mukogawa Womens Univ, Fac Pharmaceut Sci, Nishinomiya, Hyogo 6638179, Japan
关键词
D O I
10.1246/cl.1998.1089
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A uniform-sized molecularly imprinted polymer (MIP) for beta-estradiol has been prepared using 4-vinylpyridine and ethylenedimethacrylate as a functional monomer and cross-linker, respectively. The molecular recognition properties of the MIP were evaluated by HPLC using a mixture of phosphate buffer and acetonitrile as the eluent. The MIP showed the highest selectivity for beta-estradiol. The MIP could efficiently separate estrogens from other steroids such as testosterone and corticosterone, and could separate estrogens one another.
引用
收藏
页码:1089 / 1090
页数:2
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